An upside-down LCD is usually fixed by changing the rotation setting in the monitor menu or the operating system.
Start with the display's own menu
Hit the on-screen display buttons and hunt for Rotation, Orientation, or Flip under Display or Setup. If your screen is ceiling-mounted for a booth or a DJ riser, a 180-degree flip here keeps the monitor scaler clean.
If you do not see a rotation option, the panel firmware is likely locked to landscape. That is common on budget or rental monitors that only allow 90-degree steps or none at all.
Use the system menu for a fast flip
When the monitor menu is missing or blocked, the operating system can rotate the whole desktop. Open Display settings from the desktop, select the correct screen if you have multiple displays, set Display orientation to Landscape (flipped) or Portrait (flipped), and click Keep changes to lock it in.
This is the cleanest fix for a stage PC driving an upside-down projector or a vertical LED stack.
Rotation vs. reality: viewing angles and polarization
A rotated screen can look off even when the pixels are correct. TN panels are notorious for color and brightness shifts in portrait, while IPS stays steadier, so check panel viewing angles before you commit to a vertical layout.
Polarization can also bite you. Some LCDs are optimized around a 45-degree polarizer, so a flip can darken the image through polarized sunglasses, as explained in this polarization angle discussion. If your crew wears shades, do a quick tilt test before showtime.

Embedded LCDs: when the menu doesn't exist
Small character LCDs and some TFT modules do not expose rotation at all, which means the fix is physical or firmware-level. In many hobby-grade modules, there is no built-in flip option, so plan the mounting early.
Example: a 16x2 status LCD on a rack unit might require a ribbon cable flip or a driver register change if the controller supports it. That is a lot easier to handle before you bolt it into a case.

Quick calibration after the flip
Rotation changes how your eyes perceive brightness, so do a quick tune-up. Calibration is per unit, so do not copy someone else's settings, especially after a physical re-mount.
Lower the backlight until blacks stay deep but readable, raise contrast until whites keep texture instead of glare, then recheck brightness for text comfort at about 2 ft. That keeps the image punchy for party visuals without cooking your eyes.